深圳佰森生物科技有限公司  

1  呋塞米杂质A/B/C/D/E：AFurosemide Imp. A (EP)等
2  禁发 ***吡格列酮杂质：吡格列酮杂质A/B/C/D/E (EP)     亚氨基匹格列酮： Pioglitazone Imino Impurity
                                   5-(4-氟苄基)-2,4-噻唑烷二酮： Pioglitazone Fluoro Impurity
                                   吡格列酮代谢物M1/M2/M3/M4/M5： Pioglitazone Metabolite M1/M2/M3/M4/M5
3 西地那非杂质:    西地那非酰胺杂质:Sildenafil Amide Impurity   
                             西地那非酰胺杂质出现被限制词语:Sildenafil Amide Impurity Hydrochloride
                             西地那非氯杂质:Sildenafil Chloro Impurity
                             西地那非酰胺杂质：Sildenafil Carboxamide Impurity
                             西地那非内酰胺杂质：Sildenafil Lactam Impurity
                             西地那非氯杂质：Sildenafil Chlorosulfonyl Impurity
4 马来酸噻吗洛尔杂质：马来酸噻吗洛尔杂质A/B/C/D：Timolol Maleate impurity A/B/C/D
5  茶碱乙二胺杂质:   茶碱乙二胺杂质A/B/C/D/F：Theophylline-Ethylenediamine Imp. A /B/C/D/F
6  四氢禁发产品名杂质:  四氢禁发产品名杂质A/B/C/E: tetrazepam ipurity A/B/C/E
7  磺胺甲出现被限制词语杂质: 磺胺嘧啶杂质A/B/C/D
8  禁发 ***西酞普兰杂质: 西酞普兰杂质A/B/C/D/E/F: Citalopram Hydrobromide Imp. A/B/C/D/E/F (EP)
9  霉酚酸酯杂质: 霉酚酸酯峰鉴别: Mycophenolate Mofetil for peak identification
                           霉酚酸酯杂质A/B/C/D/E/F/G/H:Mycophenolate Mofetil impurity A/B/C/D/E/F/G/H(EP)
10 依达拉奉杂质:依达拉奉杂质A/B/C:edaravone impurity A/B/C
  

1 克霉唑杂质：

        克霉唑杂质A /B/C/E/F：Clotrimazole Imp. A/B/C/E/F (EP)

       克霉唑有关物质A ：Clotrimazole Related *pound A (o-chlorophenyl)diphenylmethanol

2 安立生坦杂质：

         安立生坦杂质A/B/C/D：ambrisentan impurity A/B/C/D

3 萘普生杂质：

         萘普生杂质A/B/C/D/E/F/H/I/J/K/L/M/N:Imp. A/B/C/D/E/F/H/I/J/K/L/M/N (EP)

4 阿那曲唑杂质：

         阿那曲唑二聚体：Anastrozole Dimer Impurity

        阿那曲唑杂质A /B/C/D/E：Anastrozole impurity A/B/C/D/E

5 埃索美拉唑钠杂质：

         埃索美拉唑钠杂质：H168/66   埃索美拉唑钠杂质：H193/61

        埃索美拉唑钠杂质：H431/41   埃索美拉唑钠杂质：H215/01

        埃索美拉唑钠杂质：H118/87

6 卡培他滨杂质：

         卡培他滨杂质A/B/C：Capecitabine Related *pound A/B/C

7 伐昔洛韦杂质:

        阿昔洛韦杂质A/B/C/D/E/F/G：Valaciclovir impurity A/B/C/D/E/F/G

8 苯妥英钠杂质:

        苯妥英钠杂质A/D/E:phenytoin sodium impurity A/D/E

        苯妥英钠杂质B：Diphenylethanedione(Benzil)

        苯妥英钠杂质C：Amino(diphenyl)acetic Acid (2,2-Diphenylglycine)

9 利培酮杂质：

         利培酮杂质A/B/C/D/F/H/L：Risperidal impurity A/B/C/D/F/H/L

10 依托芬那酯杂质：

         依托芬那酯杂质 A/B/C/D/E/F/G：Etofenamate impurity A/B/C/D/E/F/G

1 塞来昔布杂质：
           塞来昔布杂质A/B/C/D/E/F/G：Celecoxib impurity-A/B/C/D/E/F/G
2 文法拉辛杂质：
          文法拉辛杂质A/B/C/D/E/F/G/H：Venlafaxine impurity A/B/C/D/E/F/G/H (EP) as Hydrochloride
3 乙酰半胱氨酸杂质：
          乙酰半胱氨酸杂质A ： Imp. A (EP): L-Cystine         乙酰半胱氨酸杂质C：Imp. C (EP): N,N’-Diacetyl-L-cystine  
         乙酰半胱氨酸杂质B ： Imp. B (EP): L-Cysteine         乙酰半胱氨酸杂质D：Imp. D (EP): N,S-Diacetyl-L-cysteine
4 罗库溴铵杂质：
         罗库溴铵杂质A/B/C/D/E/F/G/H：Rocuroniumbromide impurity A/B/C/D/E/F/G/H
5 伏格列波糖杂质：
         伏格列波糖杂质：Tetrabenzyl Voglibose          伏格列波糖杂质 ：Tetrabenzyl Voglibose HCl
         伏格列波糖杂质：Tetrabenzyl Cycloketone ("TBC")
6 恩曲他滨杂质：
         恩曲他滨杂质A/B/C/D：Emtricitabine impurity A/B/C/D
7 二丙酸倍氯米松杂质：
         二丙酸倍氯米松杂质A/B/C/D/E/F/G/H：beclomethasone dipropionate impurity A/B/C/D/E/F/G/H
8 头孢哌酮杂质：
         头孢哌酮杂质A/C：Cefoperazone impurity A/C                     2-羟基奥洛他定杂质：2- hydroxyl olopatadine hydrochloride impurity
         头孢哌酮钠杂质A/B/C：Olopatadine Hydrochloride impurity A/B/C
9 硝苯地平杂质：
        硝苯地平杂质A /B/C/D：Imp. A/B/C/D (EP)
        硝苯地平杂质：2-Nitrobenzaldehyde
10 磷酸氟达拉滨杂质：
        磷酸氟达拉滨杂质A/B/C/D/E/F/G/H/I/J：salbutamol sulphate impurity A/B/C/D/E/F/G/H/I/J
11  禁发 ***醋丁洛尔杂质：
         禁发 ***醋丁洛尔杂质A/B/C/D/E/F/G/H/I/J/K
12  醋氯芬酸杂质：
         醋氯芬酸杂质A/B/C/D/E/F/G/H/I
13 阿苯达唑杂质：
          阿苯达唑杂质A/B/C/D/E
14 阿斯巴甜杂质：
         阿斯巴甜杂质A：2-(5-Benzyl-3,6-dioxopiperazin-2-yl)acetic Acid  
         阿斯巴甜杂质B：L-Aspartyl-L-phenylalanine
         阿斯巴甜杂质C：Phenylalanine
15 禁发 ***胺碘酮杂质：
         禁发 ***胺碘酮杂质A/B/C/D/E/F/H
         禁发 ***胺碘酮氮氧化物:Amiodarone N-Oxide Hydrochloride
16 丙戊酸钠杂质:
         丙戊酸钠杂质A：Pentanoic Acid (Valeric Acid)
         丙戊酸钠杂质B：(2RS)-2-Ethylpentanoic Acid
         丙戊酸钠杂质C：：(2RS)-2-(1-Methylethyl)pentanoic Acid        
         丙戊酸钠杂质D： 2,2-Dipropylpentanoic Acid
         丙戊酸钠杂质E：Pentanamide (Valeramide)
         丙戊酸钠杂质F：2-Propylpentanamide
         丙戊酸钠杂质G：2,2-Dipropylpentanamide
17 禁发 ***阿呋唑嗪杂质：
          禁发 ***阿呋唑嗪杂质A/B/C/D/E
          阿呋唑嗪系统适应性：Alfuzosin for system suitability
          阿呋唑嗪系统适应性混合物：Alfuzosin System Suitability Mixture
18  兰索拉唑杂质：
          兰索拉唑杂质A/B/C/D/E/F
          兰索拉唑枫氮氧化物   ：   Lansoprazole Sulphone N-Oxide   
19  禁发 ***维拉帕米杂质：
          禁发 ***维拉帕米杂质A/B/C/E/F/G/H/I/J/K/L/N/O
20  禁发 ***氨溴索杂质:：
          禁发 ***氨溴索杂质A/B/C/D/E：Imp. A B/C/D/E(EP)
          反式禁发 ***氨溴索杂质：trans-4-Aminocyclohexanol Hydrochloride 
          顺式禁发 ***氨溴索杂质：cis-4-Aminocyclohexanol Hydrochloride
21  伏立康唑杂质：
          伏立康唑杂质A：1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone
          伏立康唑杂质B：rac 5-Desfluoro Voriconazole
          伏立康唑杂质C：4-Ethyl-5-fluoropyrimidine
          立康唑杂质D    ：ent-Voriconazole
          伏伏立康唑杂质E：(+/-)-10-Camphorsulfonic acid 
22  阿奇霉素杂质：
          阿奇霉素系统适应性：Azithromycin for system suitability
          阿奇霉素杂质A/B/C/D：Azithromycin impurity A /B/C/D
          阿奇霉素杂质E：N',N'-Di(desmethyl)Azithromycin
          阿奇霉素相关物质F：Azithromycin Related *pound F 
          阿奇霉素Gx（阿奇霉素杂质H）：Azithromycin Related *pound H
          阿奇霉素杂质I/J：Azithromycin impurity I/J
          阿奇霉素杂质M：3'-(N,N-didemthyl)-3'-N-formlazithromycin 
          奇霉素杂质N：3'-de(dimethylamino)-3'-oxoazithromycin
         阿红霉素A偕亚胺醚：Erythromycin A Iminoether
         阿奇霉素峰值检测：Azithromycin for peak identification 
         阿奇霉素鉴别混合物：Azithromycin Identification Mixture
23  卡托普利杂质：
          卡托普利杂质A/C/D/E/J/K/N
24   氨氯地平杂质：
            氨氯地平杂质A /B/C/D/E/F/G/H
25    安非他酮杂质：
             安非他酮杂质A/B/C/D/E/F    
         
         

1 比索洛尔杂质：

     比索洛尔杂质A：(RS)-1-(4-Hydroxymethylphenoxy)-3isopropylaminopropan-2-ol

     比索洛尔杂质B：(RS)-1-Isopropylamino-3-[4-(2-propoxyethoxymethyl)phenoxy]propan-2-ol

     比索洛尔杂质C：(RS)-1-[4-[4-(2-Hydroxy-3-isopropylaminopropoxy)benzyl]-phenoxy]-3-isopropylaminopropan-2-ol

     比索洛尔杂质E：Dehydroxy Bisoprolol

     比索洛尔杂质G：(2RS)-1-[4-[[(2-Isopropoxyethoxy)methoxy]methyl]phenoxy]-3-isopropylaminopropan-2-ol

     比索洛尔杂质J：(2RS)-3-[4-((2-Isopropoxyethoxy)methyl)phenoxy]-1,2-propanediol

     比索洛尔杂质K：2-Isopropoxyethyl 4-[[(2RS)-2-Hydroxy-3-(isopropylamino)propyl]oxy]-benzoate (Bisoprolol Ester)

     比索洛尔杂质L：4-[[(2RS)-2-Hydroxy-3-(isopropylamino)propyl]oxy]benzaldehydeHydrochloride (4-[(2RS)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzaldehydeHydrochloride)

     比索洛尔杂质M：4-[(2-Isopropoxyethoxy)methyl]phenol

     比索洛尔杂质N：[(2RS)-1-[4-[(2-Ethoxyethoxy)-methyl]phenoxy]-3-isopropylaminopropan-2-ol

     比索洛尔杂质Q：(2RS)-1-(Isopropylamino)-3-[4-(2-methoxyethoxy)methyl]phenoxypropan-2-ol

     比索洛尔杂质R：(2RS)-1-(Isopropylamino)-3-(4-methylphenoxy)propan-2-ol

     比索洛尔杂质S：4-Hydroxybenzaldehyde

     比索洛尔杂质T和比索洛尔杂质U

2 比鲁卡胺杂质:

     R-比鲁卡胺:(R)-Bicalutamide     S-比鲁卡胺:(S)-Bicalutamide

     硫化比鲁卡胺 :Bicalutamide Sulfide

     比鲁卡胺亚砜:Bicalutamide Sulfoxide

     二氟比鲁卡胺:Desfluoro Bicalutamide

     双羟基比鲁卡胺:Deshydroxy Bicalutamide

     二氟比鲁卡胺异构体:2-Fluoro-4-desfluoro Bicalutamide

3 禁发 ***莫西沙星杂质:

     禁发 ***莫西沙星峰鉴别:Moxifloxacin for peak identification

     禁发 ***莫西沙星杂质A：8-Desmethoxy-8-fluoro Moxifloxacin

     禁发 ***莫西沙星杂质B：6,8-Dimethoxy Moxifloxacin Hydrochloride

     禁发 ***莫西沙星杂质C：8-Ethoxy Moxifloxacin Hydrochloride

     禁发 ***莫西沙星杂质D：8-Fluoro-6-methoxy Moxifloxacin Dihydrochloride

     禁发 ***莫西沙星杂质E：8-Hydroxy Moxifloxacin Hydrobromide

     禁发 ***莫西沙星杂质 ：Decarboxy Moxifloxacin

     莫西沙星消旋体：   ent-Moxifloxacin

4 长春西汀杂质：

      长春西汀杂质A：    Ethyl Vincaminate

      长春西汀杂质B：    Apovincamine

      长春西汀杂质C：    methoxyvinpocetine

      长春西汀杂质D：    dihydrovinpocetine

5 环孢菌素杂质：

      环孢菌素杂质A：    Cyclosporine A

      环孢菌素杂质B：    Cyclosporine B

      环孢菌素杂质C：    Cyclosporine C

      环孢菌素杂质D：    Cyclosporine D

      环孢菌素杂质H：    Cyclosporine H

6 奥美拉唑杂质：

      奥美拉唑杂质A/B/C/D/E/F/H/G/H/I：

7 禁发 ***文拉法辛杂质：

      文拉法辛系统适应性：Venlafaxine for system suitability

      去甲文拉法辛：      O-Desmethylvenlafaxine

      禁发 ***文拉法辛杂质A/B/C/D/E/F/G

8 依那普利杂质杂质：

      依那普利杂质A/B/C/D/E/F/H/G/H/I：

      依那普利系统适应性：Enalapril for system suitability

9 阿托伐他汀钙杂质：

      阿托伐他汀钙杂质A：    Desfluoro Atorvastatin Sodium Salt

      阿托伐他汀钙杂质B：    3-epi-Atorvastatin

      阿托伐他汀钙杂质C：    Difluoro Atorvastatin Sodium Salt

      阿托伐他汀钙杂质D：    Atorvastatin Epoxide

      阿托伐他汀钙杂质E：    ent-Atorvastatin

      阿托伐他汀钙杂质F：    Atorvastatin Amide Acid Sodium Salt

      阿托伐他汀钙杂质G：    3-O-Methylatorvastatin Calcium Salt

      阿托伐他汀钙杂质H：    Atorvastatin Lactone

      阿托伐他汀钙杂质I：     4-Oxo Valsartan Benzyl Ester

      阿托伐他汀甲酯：    Atorvastatin Methyl Ester

1 奥氮平杂质

     奥氮平相关杂质A       5-Methyl-2-((2-nitrophenyl)amino)-3-thiophenecarbonitrile

       奥氮平相关杂质B  5,10-Dihydro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepin-4-one

       奥氮平相关杂质C    2-methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine 4'-N-oxide

       奥氮平杂质      5,10-Dihydro-2-methyl-4H-thieno[2,3-b][1,5]benzodiazepine-4-thione

       奥氮平硫代内酰胺  Olanzapine Thiolactam Impurity

        奥氮平内酰胺        Olanzapine Lactam Impurity

      奥氮平氮氧化物        Olanzapine N-Oxide

2 缬沙坦杂质

     缬沙坦系统适应性        Valsartan for system suitability

       缬沙坦峰值检测        Valsartan for peak identification

       缬沙坦杂质A  ent-Valsartan：(R)-N-Valeryl-N-([2'-(1-H-tetrazole)-5-yl)-biphenyl-4-yl]-methyl)-valine

       缬沙坦杂质B Valsartan n-Propyl Impurity：(S)-N-butyryl-N-{[2'-(1-H-tetrazole-5-yl)-biphenyl-4-yl]-methyl}-valine

      缬沙坦杂质C    Valsartan Benzyl Ester： (S)-N-Valeryl-N-([2'-(1-H-tetrazole)-5-yl)-biphenyl-4-yl]-methyl)-valine benzyl ester

      4-羟基缬沙坦（对非对映体的混合物） 4-Hydroxy Valsartan (Mixture of Diastereomers)

    4 -羟基缬沙坦苄酯           4-Hydroxy Valsartan Benzyl Ester, Mixture of Diastereomers

    4 -羰基苄酯缬沙坦            4-Oxo Valsartan Benzyl Ester

    三苯甲基缬沙坦的N -丙基苄酯 Trityl Valsartan n-Propyl Impurity Benzyl Ester

    三苯甲基缬沙坦钠盐           Trityl Valsartan Sodium Salt

3 辛伐他汀杂质

辛伐他汀杂质A    Simvastatin Hydroxy Acid Sodium Salt

辛伐他汀杂质B    SimvastatinAcetate Ester

辛伐他汀杂质C    Anhydrosimvastatin

辛伐他汀杂质D    Simvastatin Dimer

辛伐他汀杂质E    Lovastatin

辛伐他汀杂质F    epi-Lovastatin

辛伐他汀杂质G    Simvastatin EP Impurity G

辛伐他汀酸钠盐    2,3-Dehydro Simvastatin Acid Sodium Salt

辛伐他汀甲酯       Simvastatin Methyl Ester

辛伐他汀乙酯       Simvastatin Ethyl Ester

辛伐他汀甘油酯    Simvastatin Glycerol Ester

辛伐他汀乙酸铵盐       Simvastatin Acid Ammonium Salt

4 氯沙坦杂质

氯沙坦杂质A       2-Butyl-5-chloroimidazole-4-methanol

氯沙坦杂质B [2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methanol

氯沙坦杂质C [2-Butyl-5-chloro-1-[[2'-(1Htetrazol-5-yl)biphenyl-4-yl] methyl]-1H-imidazol-4-yl]methanol

氯沙坦杂质D       2-Butyl-4-chloro-1H-imidazole-5-carbaldehyde

氯沙坦杂质E 5-(4'-Methylbiphenyl-2-yl)-1H-tetrazole

氯沙坦杂质F Losartan Isopropyl Ether

氯沙坦杂质G       Triphenylmethanol

氯沙坦杂质H       [2-Butyl-4-chloro-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]-1H-imidazol-5-yl]methanol

氯沙坦杂质I O-Trityl Losartan

氯沙坦杂质J [2-Butyl-4-chloro-1-[[2'-(1Htetrazol-5-yl)biphenyl-4-yl] methyl]-1Himidazol-5-yl]methyl Acetate

氯沙坦杂质K       Losartan Aldehyde

氯沙坦杂质I Losartan Methyl Ether

氯沙坦羧酸               Losartan Carboxylic Acid

5 卡维地洛杂质

卡维地洛杂质A    1-[[9-[2-hydroxy-3-[[2-(2-methoxyphenoxy)ethyl]amino] propyl]-9H-carbazol-4-yl]oxy]-3-[[2-(2-methoxyphenoxy) ethyl]amino]propan-2-ol

卡维地洛杂质B    3,3'-(2-(2-methoxyphenoxy)ethylazanediyl)bis(1-(9H-carbazol-4-yloxy)propan-2-ol)

卡维地洛杂质C    1-(9H-Carbazol-4-yloxy)-3-(benzyl(2-(2-methoxyphenoxy) ethyl)amino)propan-2-ol

卡维地洛杂质D    Toluene

卡维地洛杂质E    2-(2-methoxyphenoxy)ethylamine

卡维地洛杂质F    Carvedilol System Suitability Mixture (25 mg) (carvedilol spiked with carvedilol related *pound F)

8  马来酸氯苯那敏杂质:
        马来酸氯苯那敏杂质A:  Chlorphenamine Maleate Imp. A (EP) as Dihydrochloride
        马来酸氯苯那敏杂质B :Chlorphenamine Maleate Imp. B (EP)
        马来酸氯苯那敏杂质C:  Chlorphenamine Maleate Imp. C (EP) as Maleate
        马来酸氯苯那敏杂质D:  Chlorphenamine Maleate Imp. D (EP) as Maleate
 

1  马来酸氯苯
              马来酸氯苯A：Chlorphenamine Maleate Imp. A (EP) as Dihydrochloride
              马来酸氯苯B：Chlorphenamine Maleate Imp. B (EP)
              马来酸氯苯C：Chlorphenamine Maleate Imp. C (EP) as Maleate
             马来酸氯苯D： Chlorphenamine Maleate Imp. D (EP) as Maleate

2  匹多莫德杂质
            匹多莫德杂质X： Pidotimod impurity  X
            匹多莫德杂质Y：Pidotimod impurity Y：那敏杂质那敏杂质那敏杂质那敏杂质那敏杂质：